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Bio-micro-electro-mechanical system (BioMEMS)

Abstract

Bio-micro-electro-mechanical systems (BioMEMS) comprise a wide range of applications, including lab-on-a-chip devices and microfabricated implants. One project in our group investigates a hydrogel-based microfluidic device to culture and characterize breast cancer cells for screening of anti-cancer agents. By integrating traditional lab processes such as incubation and assaying in a closed lab-on-a-chip device, a much smaller number of cells, as obtained in needle biopsies, can be examined. Such a system can be used to track and characterize individual cells, and reduce the costs and time for diagnostic and drug screening assays. In another project, our group will develop flexible, polymer-based implantable microelectrode arrays for recording from neural tissue. We focus on improving the biocompatibility of the implants through surface coatings which will minimize protein adsorption and reduce tissue reaction to the implants, with applications in long-term implants for neural prosthetics.

The BioMEMS group is part of the larger Microsystems and Nanotechnology (MiNa, www.mina.ubc.ca) Research Group at UBC, which includes 17 faculty members in departments spanning Electrical, Mechanical, Chemical, and Materials Engineering as well as Physics.

Speaker Biographical Sketch

Dr. Karen Cheung received the B.S. (1998) and Ph.D. (2002) degrees in Bioengineering from the University of California, Berkeley. From 2002-2005 she was a postdoctoral researcher at the Ecole Polytechnique Federale de Lausanne in Switzerland. She is now an assistant professor at the University of British Columbia in Vancouver, Canada. Her research interests include lab-on-a-chip systems for cell culture and characterization, inkjet printing for tissue engineering, and implantable neural interfaces.

Date: 17 February 2009 (Tuesday)
Time: 2:30pm – 3:30pm
Venue: Rm G6302, 6/F, Lift 7, Academic Bldg, City University of Hong Kong,
83 Tat Chee Avenue, Kowloon Tong, Kowloon,
Hong Kong.
Fee: Complimentary
Medium of Instruction: English

For seat reservation, please call May Wong at tel (852)-2788 7379 before 14 February 2009.