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Bio-Sensing

Abstract

The 21st century is often regarded as the Century of Biology. Advances in biotechnology are expected to enhance treatments for many diseases and improve life. The application of engineering principles and solutions to biological phenomena has revealed many new opportunities. Bio-sensing is emerging an important tool as we attempt to further the understanding of many biological phenomena. This seminar will first discuss the multichannel microprobes for brain recording. Simultaneous neuron potential and neurotransmitter detection using cyclic voltammetry in olfactory mucosa of rat will be presented. An interdigitated array microprobe, using a redox cycling principle for dopamine detection, will then be discussed. An interesting example of deep brain stimulation in substantia nigra pars reticulata (SNr) and recording will be illustrated. This is followed by a discussion of bio-electronic interface integrated circuit chips for multichannel chemical (current) and potential recording. The second part of the seminar will discuss the detection of biological media. A microfluidic, filter-based microbial detection chip based on fluorescent in-situ hybridization assay will first be discussed. Quantum dots as a novel immuno-fluorescent detector for Crytosporidium parvum and Giardia lamblia will be shown. Finally, this seminar will conclude with a simple Escherichia coli O157:H7 sensor based on transduction detection principle using electrochemical impedance spectroscopy.

Speaker Biographical Sketch

Professor Simon Ang is currently a Professor of Electrical Engineering and an adjunct Professor of Biomedical Engineering at the University of Arkansas, USA. Simon graduated, with highest honors, from the University of Arkansas at Fayetteville, Arkansas, USA, with a B.S. Degree in Electrical Engineering. He subsequently completed the M.S. Degree in Electrical Engineering at Georgia Institute of Technology, Atlanta, Georgia, USA, and the Ph.D. Degree in Electrical Engineering at Southern Methodist University, Dallas, Texas, USA. Simon worked for seven years at Texas Instruments holding a variety of increasingly responsible positions including a section manager in the Advanced Power Integrated Circuit Development Center prior to joining University of Arkansas. He received numerous teaching awards and supervised over 80 M.S. and Ph.D. students in electrical engineering, biomedical engineering, agricultural engineering, and mechanical engineering. Simon received the Arkansas Alumni Association Distinguished Achievement Award in Teaching and the Insignia Award in Technology by the City and Guilds of London Institute, England, for his work on power semiconductor device development while at Texas Instruments. He is the author and co-author of more than 245 journal and proceeding articles and 6 book chapters. He is a Fellow of the Institution of Engineering and Technology (UK), the Electrochemical Society (USA), and the City and Guilds of London Institute (UK).

Date: 21 May 2009 (Thursday)
Time: 3:00pm – 4:00pm
Venue: Rm B6605, 6/F, Lift 3, Academic Bldg, City University of Hong Kong,
83 Tat Chee Avenue, Kowloon Tong, Kowloon,
Hong Kong.

For seat reservation, please fax the Registration Form to (852)-2788 7579 on / before 19 May 2009.